Open Access

Molecular Traces of the Kappa-Casein (κ-Casein) Gene in Boz Cattle: A Haplotype-Based Approach

1 Bandırma Onyedi Eylül Üniversitesi, Susurluk Tarım ve Orman Meslek Yüksekokulu, Susurluk, Balıkesir

Abstract

Theaim of this study was to analyze the κ-casein gene haplotypes in Grey Steppe breed cattle. Twenty-eight different haplotypes derived from seven SNPs were identified in Grey cattle. A two-haplotype block structure, designated as Block 1 between SNP1 and SNP3 and Block 2 between SNP5 and SNP6, was identified. Dominant haplotype combinations formed by these two blocks accounted for moret han 60% of the population. SNP4 and SNP7 were not included in the block structure. Thirteen haplotypes were observed as singletons. Of the 21 pairwise comparisons at seven polymorphic sites, 10 were found to be significant. Haplotype diversity was calculated as Hd=0.9724, nucleotide diversity (π) was 0.00409, and the mean nucleotide difference was 2.63898. The Tajima's D (2.161, P<0.05) and Fu'sFs (-19.157, P<0.05) values determined from neutrality tests were found to be statistically significant. The findings reveal that the genetic diversity of the κ-casein gene region is high in Grey Steppe breed cattle and that the variants are widely distributed in the population.

Keywords

How to Cite

KABASAKAL, A. (2025). Molecular Traces of the Kappa-Casein (κ-Casein) Gene in Boz Cattle: A Haplotype-Based Approach. ISPEC Journal of Agricultural Sciences, 9(3), 844–852. https://doi.org/10.5281/zenodo.16500540

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